Emission Tomography and Nuclear Medicine

Budinger TF and Gullberg GT. Three dimensional reconstruction in nuclear medicine emission imaging. IEEE Trans Nucl Sci NS-21(3):2-20, 1974.

Budinger TF and Harpootlian J. Developments in digital computer implementation in nuclear medicine imaging. Comp Biomed Res 8:26, 1975.

Budinger TF and MacDonald B. Reconstruction of the Fresnel coded gamma camera image by digital computer. J Nucl Med 16:309-313, 1975.

Budinger TF, Yano Y, and Hoop B. A comparison of 82Rb+ and 13NH3 for myocardial positron scintigraphy. J Nucl Med 16:429-431, 1975.

Derenzo SE, Zakland H, and Budinger TF. Analytical study of a high resolution positron ring detector system for transaxial reconstruction tomography. J Nucl Med 16:1166-1173,1975.

Hoop Jr B, Budinger TF, and Banes JW, et al. Myocardial positron scintigraphy with short-lived 82Rb. IEEE Trans Nucl Sci NS-23:584-589, 1976.

Atkins HL, Budinger TF, Lebowitz E, Ansari AN, Green MW, and Fairchild R. Thallium-201 for medical use. III:Human distribution and physical imaging properties. J Nucl Med 18(2):133-140, 1977.

Budinger TF, Cahoon JL, Derenzo SE, Gullberg GT, Moyer BR, and Yano Y. Three dimensional imaging of the myocardium with radionuclides. Radiology 125:433-439, 1977.

Budinger TF, Derenzo SE, Gullberg GT, Greenberg WL, and Huesman RH. Emission computer assisted tomography with single-photon and positron annihilation photon emitters. J Comput Assis Tomogr 1(1):131-145, 1977.

Yano Y and Budinger TF. Cyclotron-produced Zinc-62: A possible prostate and pancreas scanning agent as a 62Zn amino acid chelate. J Nucl Med 18(8):815-821, 1977.

Yano Y, Chu P, Budinger TF, Grant PM, Ogard AE, Barnes JW, O’Brien HA, and Hoop Jr B. Rubidium-82 generators for imaging studies. J Nucl Med 18(1):46-50, 1977.

Sargent TS, Braun G, Budinger TF, and Shulgin A. Brain and retina uptake of radio-iodine labeled psychotomimetic in dog and monkey. Comm in Psychopharm 2(1):1-10, 1978.

Sargent TS, Budinger TF, Braun G, Shulgin AT, and Braun U. An iodinated catecholamine congener for brain imaging and metabolic studies. J Nucl Med 19(1):71-76, 1978.

Budinger TF. Physical attributes of single photon tomography. J Nucl Med 21:579-592, 1980.

Yen C-K and Budinger TF. Evaluation of blood-brain barrier permeability changes in Rhesus monkeys and man using 82Rb and positron emission tomography. J Comput Assist Tomogr 5:792-799, 1981.

Budinger TF. Revival of clinical nuclear medicine brain imaging. J Nucl Med 22:1094-1097, 1981.

Budinger TF. Dynamic transmission computed tomography, emission tomography, and nuclear magnetic resonance methods of measuring physiologic parameters. Mayo Clinic Proc 57 (supplement):67-77, July, 1982.

Yen C-K, Yano Y, Budinger TF, Friedland RP, Derenzo SE, and Huesman RH. Brain tumor evaluation using Rb-82 and positron emission tomography. J Nucl Med 23:532-537, 1982.

Friedland RP, Budinger TF, Ganz E, Yano Y, Mathis CA, Koss B, Ober BA, Huesman RH, and Derenzo SE. Regional cerebral metabolic alterations in dementia of the Alzheimer type: Positron emission tomography [18F]fluorodeoxyglucose. J Comp Assist Tomogr 7:590-598, 1983.

Friedland RP, Mathis CA, Budinger TF, Moyer BR, and Rosen M. Labeled choline and phosphorylcholine: Body distribution and brain autoradiography: J Nucl Med 24:812-815, 1983.

Robertson JS, Price RR, Budinger TF, Fairbanks VF, and Polycove M. Radiation absorbed dose from iron-52, iron-55, and iron-59 used to study ferrokinetics. J Nucl Med 24:339-348, 1983.

Eckelman WC, Reba RC, Rzeszotarski WJ, Gibson RE, Hill T, Holman BL, Budinger TF, Conklin JJ, Eng R, and Grisson MP. External imaging of cerebral muscarinic acetylcholine receptors. Science 223:1291-1293, 1984.

Friedland RP, Budinger TF, Brant-Zawadski B, and Jagust WJ. The diagnosis of Alzheimer-type dementia: A preliminary comparison of positron emission tomography and proton magnetic resonance. JAMA 252, 19:2750-2752, 1984.

Friedland RP, Budinger TF, Koss E, and Ober BA. Alzheimer’s disease: Anterior-posterior and lateral hemispheric alterations in cortical glucose utilization. Neuroscience Letters 53:235-240, 1985.

Rosen MA, Jones RM, Yano Y, and Budinger TF. Carbon-11 choline: Synthesis, purification, and brain uptake inhibition by 2-dimethylaminoethanol. J Nucl Med 26:1422-1428, 1985.

Yano Y, Budinger TF, Ebbe SN, Mathis CA, Singh M, Brennan KM, and Moyer BR. Gallium-68 lipophilic complexes for labeling platelets. J Nucl Med 26:1429-1437, 1985.

Friedland RP, Brun A, and Budinger TF. Pathological and positron emission tomographic correlations in Alzheimer’s disease. The Lancet i:228, 1985 (Letter).

Jagust WJ, Budinger TF, Huesman RH, Friedland RP, Mazoyer BM, and Knittel BL. Methodologic factors affecting PET measurements of cerebral glucose metabolism. J Nucl Med 27:1358-1361, 1986.

Doyle WK, Budinger TF, Valk PE, Levin VA, and Gutin PH. Differentiation of cerebral radiation necrosis from tumor recurrence by F-18-FDG and Rb-82 positron emission tomography. J Comput Assist Tomogr 11:563-570, 1987.

Jagust WJ, Budinger TF, and Reed BR. The diagnosis of dementia with single photon emission computed tomography. Arch Neurol 44:258-262, 1987.

Moerlein SM, Mathis CA, Brennan KM, and Budinger TF. Synthesis and in vivo evaluation of 122I- and 131I-labelled iodoperidol, a potential agent for the tomographic assessment of cerebral perfusion. Int J Radiat Appl Instrum Part B, Nucl Med Biol 14:91-98, 1987.

Jagust WJ, Friedland RP, Budinger TF, Koss E, and Ober B. Progression of regional cerebral metabolic abnormalities in Alzheimer’s disease. Neurology 38:909-912, 1988.

Jagust WJ and Budinger TF. A comparison of positron emission tomography and single photon emission computed tomography in the study of dementia. Bulletin Clin. Neurosci, 53:51-57, 1988.

Jagust WJ, Friedland RP, Budinger TF, Koss E, and Ober B. Longitudinal studies of regional cerebral metabolic abnormalities in Alzheimer’s disease. Neurology 38: 909-912, 1988.

Moerlein SM, Dalal KB, Ebbe SN, Yano Y, and Budinger TF. Residualizing and non-residualizing analogues of low-density lipoprotein as iodine-123 radiopharmaceuticals for imaging LDL catabolism. Nucl Med Biol, Int J Radiat Appl Instrum, Part B, 15:141-149, 1988.

Valk PE, Budinger TF, Levin VA, Silver P, Gutin PH, and Doyle WK. PET of malignant cerebral tumors after interstitial brachytherapy. J Neurosurg 69: 830-838, 1988.

Friedland RP, Jagust WJ, Huesman RH, Koss E, Knittel B, Mathis CA, Ober BA, Mazoyer BM, and Budinger TF. Regional cerebral glucose transport and utilization in Alzheimer’s disease. Neurology 39:1427-1434, 1989.

Sargent III T, Kusubov N, and Budinger TF. Abnormal methyl-carbon oxidation in schizophrenia. J Cerebral Blood Flow and Metab 9 (Supp 1):137, 1989.

Valk PE, Geyer AB, Jagust WJ, Huesman RH, Derenzo SE, Cahoon JL, Vuletich T, and Budinger TF. Clinical efficacy of high resolution (2.6 mm) positron emission tomography. J Nucl Med 30:765, 1989.

Jagust WJ, Reed BR, Seab JP, Kramer JH and Budinger TF. Clinical-physiologic correlates of Alzheimer’s disease and frontal lobe dementia. American Journal of Physiological Imaging 4:89-96, 1989.

Jagust WJ, Reed BR, Seab JP, and Budinger TF. Alzheimer’s disease—age at onset and single-photon emission computed tomographic patterns of regional cerebral blood flow. Arch Neurol 47:628-633, 1990.

Valk PE, Jagust WJ, Derenzo SE, Huesman RH, Geyer AB and Budinger TF. Clinical evaluation of a high-resolution (2.6 mm) positron emission tomograph. Radiology, 176:783-790, 1990.

Budinger TF, Derenzo SE, Huesman RH, Jagust WJ and Valk PE. High-resolution positron emission tomography for medical science studies. Acta Radiologica, suppl. 376:15-23, 1991.

Jagust WJ, Seab JP, Huesman RH, Valk PE, Mathis CA, Reed BR, Coxson PG and Budinger TF. Diminished glucose transport in Alzheimer’s disease: dynamic PET studies. J Cerebral Blood Flow Metab 11:323-330, 1991.

Budinger TF. Critical review of PET, SPECT and neuroreceptor studies in schizophrenia. J Neural Transm (Suppl) 36:3-12, 1992.

Valk PE, Mathis CA, Prados MD, Gilbert JC, Budinger TF. Hypoxia in human gliomas: demonstration by PET with fluorine-18-fluoromisonidazole. J Nucl Med 33:2133-2136, l992.

Sargent T, Kusubov N, Taylor SE, and Budinger TF. Tracer kinetic evidence for abnormal methyl metabolism in schizophrenia. Biological Psychiatry 32:1078-1090, 1992.

Biegon A, Mathis CA, and Budinger TF. Quantitative in vitro and ex vivo autoradiography of the a2-adrenoceptor antagonist [3H]atipamazole. Euro J of Pharm 224:27-38, 1992.

Jagust WJ, Reed BR, Ellis WG, Eberling JL, and Budinger. Single-photon emission computed tomographic perfusion imaging in autopsy-diagnosed dementia. J Neuroimag 3:93-99, 1993.

Valk PE, Laxer KD, Barbaro NM, Knezevic S, Dillon WP, and Budinger TF. High resolution PET in partial complex epilepsy associated with mesial temporal sclerosis. Radiology 186:55-58, 1993.

Jagust WJ, Eberling JL, Richardson BR, Reed BR, Baker MG, Nordahl TE, and Budinger TF. The cortical topography of temporal lobe hypometabolism in early Alzheimer’s disease. Brain Research, 629:189-198, 1993.

Budinger TF and Taylor SE. New approaches to targeting arthritis with radiopharmaceuticals. Journal of Rheumatology, Vol 22:1 Supp 43, 1995.

Coxson PG, Brennan KM, Huesman RH, Lim S, and Budinger TF. Variability and reproducibility of rubidium-82 kinetic parameters in the myocardium of the anesthetized canine. Journal of Nuclear Medicine, Vol. 36:2, pp. 287-296, February 1995.

Eberling JL, Nordahl TE, Kusubov N, Reed BR, Budinger TF and Jagust WJ. Reduced temporal lobe glucose metabolism in aging. Journal of Neuroimaging, vol. 5:3, pp. 178-182, July 1995.

Budinger TF, Brennan KM, Moses WW and Derenzo SE. Advances in positron tomography for oncology. Nuclear Medicine and Biology, 23:6, pp. 659-667, August 1996.

Huesman RH, Klein GJ, Reutter BW, Coxson PG, Botvinick EH and Budinger TF. Strategies for extraction of quantitative data from volumetric dynamic cardiac PET data. Cardiology, vol. 88, pp. 54-61, 1997.

Marshall RC, Taylor SE, Powers-Risius P, Reutter BW, Kuruc A, Coxson PG, Huesman RH and Budinger TF. Kinetic analysis of rubidium and thallium as deposited myocardial blood flow tracers in isolated rabbit heart. American Journal of Physiology, vol. 272 (Heart and Circulatory Physiology vol. 41), pp. H1480-H1490, March 1997.

Marshall RC, Powers-Risius P, Reutter BW, Taylor SE, VanBrocklin HF, Huesman RH, Budinger TF. Kinetic analysis of 125-iodorotenone as a deposited myocardial flow tracer: comparison with 99mTc-sestamibi. J Nucl Med 42(2), 272-281, 2001.

Boutchko R, Rayz VL, Vandehey NT, O’Neil JP, Budinger TF, Nico PS, Druhan J, Saloner DA, Gullberg GT and Moses WW. Imaging and modeling of flow in porous media using clinical nuclear emission tomography systems and computational fluid dynamics. J Appl Geophys 76(1):74-81, January 2012.

Budinger TF. Future research in Alzheimer’s disease using imaging techniques. Neurobiology of Aging, 15(2):S41-S48, 1994.Jones T and Budinger TF The Potential for Low-Dose Functional Studies in Maternal–Fetal Medicine Using PET/MR Imaging. J Nucl Med.54: 2016-2017, 2013.